WebbOrganic anion transporters (OATs) are shown in red, the organic cation/carnitine transporter (OCTN/CT) family is shown in blue, and organic cation transporters (OCTs) … WebbMentioning: 17 - The aim of this study was to explore whether rhein could enhance the effects of pemetrexed (PTX) on the therapy of non-small-cell lung cancer (NSCLC) and to clarify the associated molecular mechanism. Our study shows that rhein in combination with PTX could obviously increase the systemic exposure of PTX in rats, which would be …
The organic anion transporter family: from physiology to …
WebbThe organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention … Webbic anion transporter families, e.g. the organic anion trans-porting polypeptide (oatp) family or the Mrp (multidrug resistance-associated protein) family. On the other hand, the … phillips medical group talbott
Organo anion transporter family - Wikipedia
Webb11 apr. 2024 · Glycine synthase (AMT), a solute organic anion transporter family member (OAT), and fatty acyl-coA reductase (FAR) are predicted to be regulated by multiple … WebbGene Family The human SCL22 family of transporters encompasses at least 22 members with an additional six structurally related but not yet assigned genes. ... In Vitro and In … The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6 gene. It is a member of the organic anion transporter (OAT) family of proteins. OAT1 is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells o… phillips meat packing zanesville ohio