Phnshp45
Webb16 okt. 2024 · Newport strains ASGD2 to pHNSHP45-2 revealed that this plasmid aligned very well with pHNSHP45-2 except that a region containing the tra genes, which were responsible for conjugation, was absent ... Webb5 juli 2024 · pHNSHP45 was used as a reference to compare with the pMCRs described here and with other IncI2 plasmids. The outer circle with red arrows indicates annotation …
Phnshp45
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Webb23 feb. 2024 · TEXT. The discovery of the plasmid-mediated colistin resistance gene mcr-1 has captured global attention. Unlike colistin resistance raised by chromosomal mutations, the plasmid carrying the mcr-1 resistance gene can be rapidly disseminated through horizontal gene transfer. Since the first report of plasmid pHNSHP45 carrying the mcr-1 … Webb6 feb. 2024 · Except for a 3,684 bp region that was also present in a pHNSHP45-2-like plasmid and included the ISApl1 and mcr-1, the entire nucleotide sequence showed …
WebbDownload scientific diagram Plasmid comparison of pRS1231-S-MCR-1.1 and pHNSHP45 (Accession Number: KP347127.1). From the inner to outer ring: The inner ring represents … Webb27 feb. 2024 · Plasmid pHNSHP45 in particular presented a high fitness advantage for its host, and the fitness was enhanced (16–91%) as serial passage. In contrast, plasmid …
Webb7 mars 2016 · A transferable plasmid conferring resistance to colistin was discovered in Escherichia coli and Klebsiella pneumoniae from China and was confirmed to have carbapenemase-producing properties. Colistin is considered a last resort for the treatment of infections caused by carbapenemase-producing members of the family … Webb1 juni 2024 · Global dissemination of the mobile colistin resistance mcr-1 is of particular concern as colistin is one of the last-resort antibiotics for the treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria. In this study, an inactive form of mcr-1 in a fluoroquinolone-resistant and colistin-susceptible uropathogenic Escherichia …
Webb8 jan. 2016 · [Source: The Lancet Infectious Diseases, full page: (LINK). Summary.] Correspondence Colistin resistance gene mcr-1 and pHNSHP45 plasmid in human …
Webb29 juni 2024 · 2.2. mcr-1 Inhibits pHNSHP45 Transfer through Conjugation mcr-1 is carried by the plasmid pHNSHP45, hereafter referred to as the mcr-1 plasmid. To examine whether the mcr-1 gene contributes to the transfer of pHNSHP45, we replaced the mcr-1gene with a kanamycin-resistant cassette (KmR) on pHNSHP45 to obtain the pAC22 crypto laws in singaporeWebb60 kb in-size, and were similar to pHNSHP45 (Fig. 1), the original sequenced mcr-1 plasmid published in 2015 [5]. The three IncI2 plasmids shared a common plasmid backbone, however, in the case of pPC11 the mcr-1 cas-sette [17] was located in an inverted orientation com-pared to the others (data not shown). Additionally, the crypto lawsuit secWebb28 nov. 2016 · The insertion sequence ISApl1 occurs in both pHNSHP45 and pA31-12 is absent in the plasmid pE15017, which is validated by PCR detection coupled with Sanger … cryptomibsWebb5 juli 2024 · pHNSHP45 was used as a reference to compare with the pMCRs described here and with other IncI2 plasmids. The outer circle with red arrows indicates annotation of the reference sequence. Gaps in the inner circles are missing regions when compared with the reference. Plasmids characteristics are included in Table 3. cryptomichnl twitterWebbThe Lancet Infectious Diseases 2016 16, 283-284DOI: (10.1016/S1473-3099(16)00012-8) 21 Blast comparison with pHNSHP45 showed 100% similarity only in a short, 2604 bp … crypto lawyer firmWebb6 mars 2024 · 35 China right now, we applied its 2 surrogate plasmids, pHNSHP45 and pDJB-3 36 (Fig. 1A), in the conjugation assays. In general consistency with an 37 observation of Zhi et al. 29, the efficiency of pHNSHP45-2 transfer is calculated 38 to be 3.7x10-5 in our experiment of conjugations. In contrast, pDJB-3 can’t cryptomicWebbSequence alignment of seven IncI2-type mcr-1-bearing plasmids. pHNSHP45 with GenBank no. KP347127 was used as a reference to compare with other mcr-1-bearing plasmids which possess the IncI2 replicon. crypto lawyers